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Hydroquinone is a prescription-strength bleaching agent that inhibits melanin production but carries risks including skin irritation, paradoxical darkening with prolonged use, and ochronosis with very long-term use

Most patients receive one intramuscular dose every three to four weeks, though the schedule may be shortened or extended based on symptom control and estradiol blood levels

tb burden in the lungs, decreased oxidative stress, and increased the production of IFN-, TNF-, IL-17, IL-10, and TGF-1compared to the untreated mice

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