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Room temperature storage: Stable for 6-12 months when sealed Keep below 25C (77F) Protect from direct sunlight Store in original packaging or wrap in foil Refrigerated storage (2-8C / 36-46F): Extends shelf life to 18-24 months Preferred for long-term storage Keep in main fridge section (not freezer, not door) Freezer storage (-20C / -4F): Maximum shelf life: 24-36 months Only for unopened sealed vials Thaw completely before reconstituting Don't repeatedly freeze and thaw Why lyophilized powder is stable: Freeze-drying removes water, which is necessary for degradation reactions

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We call it fighting dirty (applying over the days dirt, grime and makeup is just fine)

doi: 10.1016/j.retram.2022.103362 25 HuguenardC