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There has been a gradual uptick in Wegovy usage in Ontario between 2018 and 2025, with an academic practice in Toronto specifically noting an increase of 3.7% for patients using these types of treatments

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from Germany, in 2025, examined the oral intake of bovine-derived collagen peptides called GELITA on dermal matrix synthesis and clinical skin parameters in a randomized, double-blind, placebo-controlled trial of 66 women (aged 3555 years) [54]

Microinfusion uses ultra-fine dissolving microneedles or stamp devices to create temporary micro-channels in the skin, allowing topical actives to bypass the stratum corneum and reach the upper dermis where they can interact with fibroblasts directly