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In the nucleus, Nrf2 induces the expression of cytoprotective genes that mitigate ferroptosis by regulating iron metabolism and enhancing antioxidant defenses

Front Plant Sci 8:836

For instance, Fanconi's syndrome is a hereditary or acquired condition in which the proximal tubular reabsorption function of the kidneys is impaired (37)

These genes have been characterized into different classes such as protein kinases and phosphatases, transcription factors, enzymes, molecular chaperones, and other functional proteins