trump glp-1 announcement administration makes deal to lower prices The “Fauxzempic” Crisis: Counterfeit Innovation

As more data has become available, scientists have taken a closer look at how GLP-1 receptor agonists affect the brain

CRS arises from the excessive activation of immune effector cells and a cytokine storm triggered by CAR T-cell-induced tumor pyroptosis, which stimulates macrophages and initiates a cascade of proinflammatory cytokine release (particularly IL-6, IL-1, IFN-, GM-CSF), endothelial activation, and systemic inflammation

doi: 10.1038/s41392-023-01637-8 9 YangKWuZZhangHZhangNWuWWangZet al

Crypts were separated from the intestine by vigorous shaking 2 times and collected by centrifugation at 200 g for 5 minutes, and crypts from 3 mice were mixed at equal ratios