After 2 weeks, on follow-up, patient was afebrile and repeat levels of vitamin B12 levels were 2000 pg/l, LDH had decreased to-341 mU/ml, total bilirubin to 0.5 mg/dl (with indirect bilirubin-0.1mg/dl) and homocsyteine had decreased to12 micromoles/l
Because of this, taking more than the recommended dosage of Vitamin B-12 will neither help nor harm you unless you have an actual problem with deficiency
Bacteriostatic water ZPHC 10ml
A Cochrane review supports the use of high-dose vitamin B 12 (1 mg and 2 mg daily) in elevating serum vitamin B 12 level and achieving haematological and neurological responses, even in patients with PA or with ileal resection.58 The recommendation for oral replacement is 1 mg daily for a month, and then 125 to 250 g daily as maintenance dose for patients with dietary insufficiency and food-cobalamin malabsorption, while for PA the maintenance dose is 1 mg daily.29 Vitamin B 12 does not have side-effects even when prescribed in large doses.59 However, hypokalaemia, resulting from uptake of circulating potassium by newly growing and dividing haematopoietic cells, can be severe or sometimes life-threatening