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Furthermore, some study revealed that ADORA2A antagonism suppresses the assembly and activation of nucleotide-binding domain-like receptors protein 3 (NLRP3) inflammasome, attenuating neuroinflammation following traumatic brain injury, and confers robust neuroprotective effects against chronic high-altitude exposure-induced cognitive impairment 35,36,37
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Benkhoucha M, Santiago-Raber ML, Schneiter G, Chofflon M, Funakoshi H, Nakamura T, et al
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