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Insulin-like Growth Factor-1 (IGF-1) is a naturally occurring peptide hormone that plays a critical role in muscle growth , cell repair , fat metabolism , and anabolic signaling

Furthermore, this study revealed that a ketogenic diet supplemented with 25% 8-carbon MCTs, combined with a daily dose of the chemotherapeutic drug cyclophosphamide [40 mg/kg for mice with SH-SY5Y xenografts and 13 mg/kg for mice with SK-N-BE(2) xenografts], administered for at least 36 days, was more effective than a diet supplemented with LCTs in sensitizing neuroblastomas to low-dose chemotherapy

Therefore, an MTT assay was performed using E9 cells to assess their biocompatibility after ZNT treatment