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The best evidence for weight loss comes from a meta-analysis of 37 trials: a modest average reduction of about 1.2 kg (under 3 lbs), mostly in adults who are overweight

When Cochrane reviewers grade an evidence base as very low quality despite a positive pooled effect, this is usually what they are reacting to: not that the benefit is fake, but that the conditions under which it was measured are the conditions that reliably make benefits look bigger than they are

They are reviewing all patient-facing content, including website copy, social posts, EDMs, and treatment menus, for any reference to unapproved products or health claims that cannot be substantiated under Australian advertising rules

The sterilized suspensions are then filled into vials, which were then used to test the formulations