They work through several mechanisms that are relevant even when your pancreas no longer makes insulin: they slow gastric emptying (meaning food hits your bloodstream more gradually), suppress glucagon release (the hormone that raises blood sugar), and reduce appetite
For a country with over 10 crore adults living with diabetes and an estimated 25 crore with obesity, the price reduction represents a significant accessibility shift, creating both opportunity and risk
GLP-1 performs its biological functions through binding to GLP-1 receptor (GLP-1R), a multifunctional member of the G protein-coupled receptor family, which initiates a downstream signaling cascade [3, 4]
Lifestyle changes, primary care monitoring, FDA-approved medications, diabetes treatment, nutrition support, and chronic disease management can help now