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BPC-157 was removed from Category 2 on April 15, 2026

EMBO J 5:12211227 Brigelius-Floh R, Maiorino M (2013) Glutathione peroxidases

Although most studies have focused on AIM2 sensing of nuclear or pathogen-derived DNA, recent work suggests that mtDNA released during apoptosis or mitochondrial damage can also activate the AIM2 inflammasome, amplifying inflammation [42]