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The pre-meal timing works because it occupies stomach space, supports blood sugar stability going into a meal, and may help reduce how much you eat

Differences in baseline characteristics among the groups were assessed using the Kruskal-Wallis test for continuous variables and the chi-square test for categorical variables

L-carnitine can be directly transformed into TMA via intestinal flora-derived CntA/CntB , and also into -butyrobetaine and betaine, and further converted to TMA through the yeaW/yeaX enzyme system of intestinal flora (36)

Wegovy is administered as a once-weekly subcutaneous injection, with doses gradually increased over 16-20 weeks to minimise gastrointestinal side effects