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Starting with gentle activities such as walking for 1015 minutes daily and gradually increasing intensity can enhance cardiovascular fitness, improve mood, and reduce fatigue

While average timelines can guide protocol design, some subjects may show effects earlier or later than typical

3.2.1 PINK1/Parkin mediated mitophagy The pathway consisting of PINK1 and Parkin is a key participant in mitophagy, as well as the most common and classical pathway of autophagic mitochondria (Lazarou et al., 2015)