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GHK-Cu also promotes dermal fibroblast proliferation (MTT, CFSE dilution) and migration (scratch assay, Boyden chamber) at concentrations of 110 M
In detail, a NanoWizard 3 Bioscience with piezo range up to 15 m (JPK Instruments, Germany) was used for the shortest cell-surface contact time and a CellHesion 200 (JPK Instruments, Germany) with 100 m piezo travel length was used for longer cell-surface contact times (5 s, 10 s) in order to make sure that the cell detachment length can fully be reached with the piezo
It also participates in the methylation cycle, a process connected to functions like DNA synthesis, immune health, and hormone regulation
PBMCs stimulated with SIHUMIx, pre-exposed to BPX, showed similar activation characteristics, i.e
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