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Among them, the thiol group (-SH) on the cysteine residue is the key active site through which glutathione performs antioxidant, detoxification, and other functions

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Correlation/cluster analysis alone is not sufficient to assess critical communication pathway(s) through the receptor, however, it forms the basis of the Network and Community Analysis, where a network is formed by an ensemble of nodes (residues) that are interconnected by edges, with an edge being a pair of critical nodes

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