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Subsequently, Nuclear Factor Erythroid 2-related Factor 2 (NRF2) was identified as a transcription factor involved in regulating gene expression at these ARE sequences (Itoh et al., 1997

Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line

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Pathway 1 - Mitochondrial Fat Oxidation (AMPK) MOTS-c activates AMP-activated protein kinase (AMPK) , the energy sensor that flips muscle cells from preferring glucose to preferring fat