Common symptoms included nausea, diarrhea, and vomiting, which subsided as the body adjusted to the treatment
Patients should seek urgent medical attention if they experience: Severe or persistent abdominal pain (possible pancreatitis or gallbladder complication) Signs of dehydration (dizziness, reduced urine output) due to vomiting or diarrhoea Symptoms of hypoglycaemia (shakiness, sweating, confusion) or hyperglycaemia (excessive thirst, frequent urination) Severe headache or visual disturbance (possible raised intracranial pressure) Signs of an allergic reaction (rash, swelling, difficulty breathing) Regular monitoring should include fasting glucose, HbA1c, IGF-1, lipid panels, liver function, and renal function
The cardioprotective effects of mesenchymal stem cells, GLP-1RAs or pioglitazone may improve mitochondrial function via regulating autophagy and inflammatory signaling [87]
These microbiome alterations are associated with greater intestinal barrier integrity, decreased endotoxemia, and increased synthesis of short-chain fatty acids
