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On 21 May 2026 , Lilly published the long-awaited topline results from the TRIUMPH-1 Phase 3 trial, and the data is striking: participants on the highest dose lost an average of 28.3% of their body weight at 80 weeks , with 45.3% of patients losing 30% or more a threshold previously only achievable with bariatric surgery

Tsou SH, Luo KS, Huang CN, et al

Thus, females are more sensitive than males to the effect of dietary modifications, as compared with that of surgery, on hepatic triglycerides

Both are injectable medications that can support weight loss, but they work in slightly different ways and may be better suited for different individuals