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What sets GHK-Cu apart in the research literature is scale: naturally occurring levels of the peptide in human plasma decline from roughly 200 ng/mL at age 20 to about 80 ng/mL by age 60, a drop researchers have used as a starting point for studying its potential connection to age-related changes in tissue repair

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10,14 Some studies have pointed out that there can be associated structural changes in the brain of PACS patients such as a reduction in global brain size, loss of gray matter thickness, and tissue contrast in the parahippocampal gyrus and orbitofrontal cortex, as well as tissue damage to the primary olfactory cortex 15 (Figure 1)

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