does semaglutide cause mood changes GLP-1 Changes: Side Effects & What to Expect Emotional Numbness on Ozempic -

The standard dosing schedule is what ships with your medication, and getting individualized adjustments is difficult given the limited access to providers through the platform

No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance

Figure 1 below depicts the incretin effect in a normal patient versus a diabetic patient

Mutat Res Genet Toxicol Environ Mutagen 836:3641 Dioni L, Hoxha M, Nordio F, Bonzini M, Tarantini L, Albetti B, Savarese A, Schwartz J, Bertazzi PA, Apostoli P, Hou L, Baccarelli A (2011) Effects of short-term exposure to inhalable particulate matter on telomere length, telomerase expression, and telomerase methylation in steel workers