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Circulating soluble leptin receptor and free leptin index during childhood, puberty, and adolescence

This simplifies the treatment regimen for patients and may improve adherence compared to more frequent dosing schedules

Similar facial changes occur after bariatric surgery, extreme dieting and illness

Clinical criteria that must be documented for approval of a PA request for lipotropics, PCSK9 inhibitor drugs for members with HoFH are all of the following: Note: For PA requests for non-preferred lipotropics, PCSK9 inhibitor drugs, the member must have taken a preferred lipotropics, PCSK9 inhibitor drug concurrently with maximized LDL-lowering therapies for at least three continuous months with failure to reach an LDL less than or equal to 130 mg/dL