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Building upon ADAR2-associated RNA editing, one recent study developed AAVs that co-express the wild-type human ADAR2 catalytic domain fused to bacteriophage N peptide (Editase wt ) and Mecp2 -targeting guide RNAs [114]

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C.GolzE.SundvickK.KligerD.RadisavljevicN.et al (2020)

In the United States, nearly 70% of adults are grappling with obesity or overweight conditions, which are significant contributors to some of the leading causes of mortality, including heart disease