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Description

Murphy, C., Barrington-White, H., Pomeranc, A

As diclofenac metabolites are eliminated primarily by the kidney, patients with renal insufficiency close monitoring of the patient's renal function is advisable

Once both substrates are bound at the enzyme's active site, the monomeric GST interacts with another substrate-bound GST monomer and catalyzes a disulphide bridge between the two glutathione molecules