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In addition, these hormones are rapidly (within minutes) broken down by the enzyme dipeptidyl peptidase-4 (DPP-4), which poses an obvious problem for their potential therapeutic use

[DOI] [PubMed] [Google Scholar] 27.Baker B.H., Lugo-Candelas C., Wu H., Laue H.E., Boivin A., Gillet V., Aw N., Rahman T., Lepage J., Whittingstall K., et al