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Clinical trial results overview Phase 2 trial outcomes: Eli Lilly's phase 2 trials demonstrated dose-dependent weight loss reaching 24.2% at the highest doses over 48 weeks

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However, it is important to note that further research and high-quality clinical trials are needed to establish the true efficacy of natural GLP-1 inducers and to determine if their effectiveness is comparable to that of GLP-1 drugs

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Future investigations should incorporate models of fibrous-cap thinning, plaque instability, and rupture-prone lesions to determine whether GLP-1RAs protect the full spectrum of atherosclerotic progression

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