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Specific transport proteins, such as organic anion transporting polypeptides ( OTAP1B1 and OATP1B3 ), actively facilitate the transfer of bilirubin from the sinusoidal blood into hepatocytes [24]

L.GardnerJ.DawsonG.et al (2003)

The physical symptoms of addiction withdrawal are as follows: Sweating and chills : The autonomic nervous system becomes hyperactive during drug withdrawal, producing alternating hot and cold sweats