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In a recent large cross-sectional study evaluating 9823 T2DM patients from around the world (including Brazil), 34.8% of patients had established cardiovascular disease (CVD), of whom 85.8% had atherosclerotic cardiovascular disease (ASCVD) [8]

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Abbreviations CMV: Cytomegalovirus GWAS: Genome-wide association studies HBV: Hepatitis B virus HIV: Human immunodeficiency virus HLA: Human leukocyte antigen HO1: Heme oxygenase 1 MART-1: Melanoma antigen recognized by T cells 1 MHC: Major histocompatibility complex NB-UVB: Narrow-band UVB NLRP1: NLR family pyrin domain containing 1 NPY: Neuropeptide Y PDGFRB: Platelet-derived growth factor receptor ROS: Reactive oxygen species SIRT1: Sirtuin 1 TRP: Tyrosinase UTR: Untranslated region XBP1: X-box binding protein References Akbayir N, Gokdemir G, Mansur T, Sokmen M, Gndz S, Alkim C, Barutcuoglu B, Erdem L