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Lignin-based nanomaterials including hydrogels and 3D bioprinting scaffolds have shown low cytotoxicity, high mechanical stability, and wide applicability in tissue engineering [144]

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7 patients with migraine episodes and vasomotor headaches, chronic tinnitus and psychogenic pain attacks were studied, and after intravenous administration on 5 consecutive days followed by 5 injections every 48-72 h, DSIP lowered the pain levels of 6 out of 7 patients significantly

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