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Understanding the unique properties of these analogs could lead to more effective and safer interventions for cognitive decline in aging populations
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Un mecanismo complementario descrito es la activacin de la va Src-Caveolina-1-eNOS: BPC-157 fosforila Src y Cav-1, reduce la unin Cav-1/eNOS y libera eNOS para generar xido ntrico, modulando el tono vasomotor (PMID 33051481)
Lin SH, Zhang N, Godby J, Wang J, Marsh GD, Liao Z, Komaki R, Ho L, Hofstetter WL, Swisher SG , Mehran RJ, Buchholz TA, Elting LS, Giordano SH
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