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Non-immunological adverse drug reactions Non-immunological ADRs caused by antibiotics include: Infection with other organisms such as yeasts (eg, oral candidiasis or vulvovaginal candidiasis due to broad-spectrum antibiotics, or Malassezia folliculitis or Gram-negative bacterial folliculitis due to long-term treatment with a tetracycline)

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Tumor growth is driven by intricate interactions between the tumor microenvironment (TME) and immune cells, inflammatory mediators, extracellular matrix remodeling, hypoxia, cancer stemness, cellular senescence, and metabolic dysregulation