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By binding to these receptors, estrogens and estrogen-like molecules modulate cell proliferation (Gompel et al., 2004

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These immunomodulatory effects were abolished in mice lacking GLP-1R in the Cdh5 domain, which targets the endothelial lineage, but remained intact in myeloid-targeting Glp1r Lyz2/ mice

It's marketed under brand names including Ozempic (injectable for diabetes), Wegovy (injectable for weight management), and Rybelsus (oral tablet for diabetes)