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The inhaled silica particles can be directly phagocytosed by alveolar macrophages (AMs), and thereby triggers NLRP3 inflammasome activation and IL-1 production, which results in a cascade release of proinflammatory and profibrotic cytokines, i.e., IL-6, tumor necrosis factor (TNF-) and TGF-1

Plasma coenzyme Q 10 concentration one month after angioplasty was positively correlated with less inflammation and oxidative stress and predicted favorable left ventricular end-systolic volume remodeling at six months (44)