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7.4.1.4 Insulin-like growth factor-1 (IGF-1) IGF-1 is a potent neurotrophic factor that is involved in the regulation of neuronal growth and survival

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Without sufficient B12, this sheath can weaken, which may explain symptoms such as tingling, numbness, memory issues, or brain fog. From an energy standpoint, B12 supports the methylation cycle , a chemical pathway involved in energy metabolism and detoxification