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Chronic and recurring infections, altered adipose tissue metabolism, intestinal dysbiosis, increased synthesis and impaired clearance of pro-inflammatory cytokines, oxidative stress, and acidosis are some of the variables that lead to chronic inflammatory status in CKD

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The control group received saline, the negative control was injected with cyclophosphamide only, and the positive control received cyclophosphamide along with mesna while the test group received boswellic acid at concentrations of 100 and 200 mg per kg before cyclophosphamide administration