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Higher cumulative weekly exposure may intensify these effects beyond the tolerability data from once-weekly clinical trials

[29] [54] Mechanism of action [edit] Semaglutide is a glucagon-like peptide-1 receptor agonist

30 HernndezJ

Furthermore, potential predictors of affective switching with antidepressants may include bipolar I disorder (versus bipolar II), mixed features during depression, tricyclics and partly dual-action inhibitors versus modern antidepressants [26], rapid cycling and possibly a history of drug abuse, especially stimulant abuse [27]