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For instance, in oral pills, the retention is not extended, with little absorption

This was demonstrated for the endogenous MOR in striatal neurons (Haberstock-Debic et al., 2005) and occurred mainly in dendrites (Haberstock-Debic et al., 2003), in the human neuroblastoma cells SH-SY5Y (Nowoczyn et al., 2013) and in double KO MEF for arrestins transfected both with MOR and arrestin 3 (Groer et al., 2011)

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The program GraphPad Prism 9.3.1 (GraphPad Software, San Diego, CA, USA) was used to verify normal distribution of data by ShapiroWilk normality test and to compare groups with one-way ANOVA followed by Bonferroni post-test