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Stockwell, B.R., J.P

There is a known relationship between AMPK and SIRT1, in which deacetylase is required for the activation of liver kinase B1 (LKB1), which phosphorylates the -AMPK subunit

Topical antihistamine creams are not recommended for this purpose, as they carry a risk of contact sensitisation and are not supported by UK clinical guidance (BNF