glp 1 constipation and diarrhea on a GLP-1 is common, predictable, manageable. Here's what's driving it and what to do about it. #obesitymedicine #womenshealth #obesitydoctor​​​​​​​​​​​​​​​​ Struggling with GLP-1 therapy side

NR1H4 not only controls intestinal barrier integrity, prevents bacterial translocation, maintains gut microbiota homeostasis, but also regulates the expression of genes involved in cholesterol and bile acid homeostasis, hepatic gluconeogenesis, adipogenesis, inflammation, and fibrosis [73]

Because I think now we have pretty strong data, 3 very large randomized controlled trials, part of the COSMOS trials

Lipase may support an evaluation for pancreatitis when characteristic abdominal pain is present

Experiments indicate that PKA is the predominant and most physiologically relevant effector through which beta agonists cause bronchial smooth muscle relaxation (Morgan et al, 2014)