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Tissue collection EDTA-anticoagulated peripheral blood was collected via submandibular vein bleeding before therapy initiation and 3 h after the last aCD3 injection and immediately processed (see 'Haematology and spectral flow cytometry analysis')

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While both drugs help control blood glucose levels, transitioning between them requires careful dose adjustment due to their different mechanisms of action and dosing regimens

As expected from the TAM chow avoidance, mice that received TAM chow weighed less than vehicle chow-fed mice at the end of chow exposure, although this pattern only reached significance in the male mice (female: 16.65 0.26 g veh chow vs 15.52 0.31 g TAM chow