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Cell 104 , 165172 (2001)

Interestingly, when FOXO4 expression was silenced in TM3 cells using siRNA prior to H2O2 treatment, cell viability decreased, and apoptosis increased, despite elevated p53 levels

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analyzed the correlation between the diet of UC patients in remission and their gastrointestinal symptoms, indicating that a higher consumption of lycopene was correlated with a lower incidence of fecal blood in these patients, whereas another similar study by the same research group reported no significant association between lycopene intake and the decreased occurrence of constipation in UC patients (Gbska et al., 2016