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19 The trial was stopped after interim analysis showed a significant reduction in the composite endpoint of end-stage kidney disease, doubling of serum creatinine level and death from renal or cardiovascular causes

Plasma levels of total GLP-1 and GIP before and during oral glucose tolerance test (oGTT) were not affected or tended to be higher in Kcnj11 / mice than those in control mice (Figure 1C)