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The mean increase in clinical trials (at any visit) was one to four beats per minute, but 26% experienced an increase of 20 beats per minute or more

Contact your healthcare provider if you notice: Redness or swelling that continues to spread Warmth, pus, or other signs of infection A lump that doesnt improve after about a week Pain thats severe or continues to get worse Read more: How to manage injection site reactions What to do if medication leaks out of the injection site A small drop of medication on your skin after an injection is usually not a cause for concern

Our data sources included PubMed and Web of Science, with search terms such as GLP-1RAs, liver, MASLD, HCC, inflammatory, microbiota, metabolism, and their combinations

The hierarchy of the pre-appraised evidence pyramid was used to obtain information