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In line with this, chronic low-dose treatment with LPS increases food intake, decreases CCK-induced satiety, and causes vagal afferent leptin resistance in rats 264

Fiber influences the secretion of key metabolic hormones including GLP-1 (glucagon-like peptide-1) and PYY (peptide YY), both of which play crucial roles in appetite regulation and insulin sensitivity

PubMed Central, Wang, Liang-Jen, et al

"There's a lot of research that's being done to try to be supportive and create assurances around that." The FDA also cites a lack of evidence that these compounds really work