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Scientifically, menopause triggers a sharp drop in estrogen, leading to vulvovaginal atrophy (thinning and drying of tissues), while chronic stress activates the hypothalamic-pituitary-adrenal axis, inhibiting arousal pathways and diverting energy from reproduction to survival.[5][9] Key contributors include: Menopause and perimenopause: Estrogen drop thins vaginal tissues, reduces lubrication, and dampens libido by altering brain chemistry
It outperformed both retinol and vitamin C in at least one head-to-head comparison
This is stress response to rapid weight loss and caloric restriction, not direct medication effect
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