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doi: 10.3389/fendo.2025.1562653 Received 17 January 2025 Accepted 31 March 2025 Published 17 April 2025 Volume 16 - 2025 Edited by Prem Prakash Kushwaha, Case Western Reserve University, United States Reviewed by Ankit Kushwaha, Stanford University, United States Saurabh Mishra, Cleveland Clinic, United States Updates Copyright 2025 Zong, Wang, Chen, Fang and Zhang

Additionally, a recent study (198) suggests that R-SH, an OSM, could serve as a biomarker for IBD, proving more sensitive than C-reactive protein (CRP) in detecting moderate endoscopic activity, though less sensitive than fecal calprotectin, with age and albumin levels as potential confounding factors, and indicates that R-SH may improve IBD monitoring

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