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Paclitaxel is the most commonly used drug across cancer types, especially in BC, prostate cancer and lung squamous cell carcinoma, and is often combined with chlorpromazine and carboplatin

On the basis of theoretical considerations, it was hypothesized that the operon encodes for a malic semialdehyde dehydrogenase (MSA-DH) which enables for the subsequent conversion of MSA into L-malate which might be channelled into the tricarboxylic acid cycle (Zhu et al., 2014)

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Unlike oral medications, subcutaneous tirzepatide injection bypasses the digestive system entirely, making food intake irrelevant to drug absorption and effectiveness