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It's a tiny 16-amino-acid peptide that your own body actually encodes, inside the mitochondrial 12S rRNA gene, and researchers have been looking at it for metabolism, insulin sensitivity, and the AMPK energy pathway

Medical and Surgical Treatment of Reproductive Outcomes in Polycystic Ovary Syndrome: An Overview of Systematic Reviews

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however, this pattern shifted in 2023 when both T2DM and the second most common diagnosis, hypertension, were surpassed by obesity (47.1%)