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Current evidence doesnt point to a specific causal relationship that directly links GLP-1 drugs and microbial overgrowths, but the underlying mechanics and possible resulting effects certainly warrant a degree of caution

In Vitro GLP-1R agonist 2 (100 nM, 1,000 nM) activates GLP-1 receptor-mediated cAMP production, with an EC 50 of 101 nM, but exhibits a self-limiting effect at high concentrations [2]

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