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10.8%, RR 4.44, 95% CI: 1.6112.21) and live birth rate (40.0 vs

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Both of these effects were canceled in the presence of an antagonist of melanocortin receptors 3 and 4, confirming receptor-mediated mechanisms

Although THC possesses neuroprotective antioxidant properties through non-CB1R pathways [33], it also upregulates plasma inflammatory cytokines [34], increases vulnerability to ischemic stroke in young people [35], increases mitochondrial dysfunction [36, 37] and alters gene pathways associated with mitochondrial oxidative phosphorylation [38]