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Research Applications Researchers can investigate: Extracellular matrix remodeling (GHK-Cu) Inflammatory signaling modulation (KPV) Angiogenesis and vascular repair (BPC-157) Cellular migration and tissue organization (TB-500) This multi-peptide approach allows for hypothesis testing on combined pathways rather than studying each peptide in isolation protidehealth.com+1

The uptick in NAION-related lawsuits follows the publication of a June 2025 study in JAMA Ophthalmology , which found a significant association between semaglutide use and increased risk of optic nerve damage